The hospital  built in 1757 was one of the works built on the orders of Bishop Juan Manuel Rodríguez  Castañón and was erected on the same site as the medieval hospital.  As well as the building providing a place of care and assistance, it also housed notary offices and the church prison on the lower  floor. On the two upper floors  and arranged around a baroque style patio,  there were separate  areas for  treating male and female patients;  a chapel;  the administrator’s  rooms;  the doctor’s Surgery, as well as the kitchen.

Among the pieces of this museum, they count the five panels with the fourteen sambenitos, unique in Spain. These valuable historical documents, restored and hung now together on a wall, correspond to specific people, heretics prosecuted before the court of the Inquisition (17th century).